Sodium bicarbonate controversy in lactic acidosis.
نویسندگان
چکیده
1 Barst RJ. Experience and reason [editorial]. Chest 2000; 117:2–5 2 Klings ES, Hill NS, Ieong MH, et al. Systemic sclerosisassociated pulmonary hypertension: shortand long-term effects of epoprostenol (prostacyclin). Arthritis Rheum 1999; 42:2638–2645 3 Klings ES, Ieong MH, Simms RW, et al. Long-term intravenous epoprostenol therapy for pulmonary hypertension associated with systemic sclerosis [abstract]. Am J Respir Crit Care Med 2000; 161:A459 4 Humbert M, Sanchez O, Fartoukh M, et al. Treatment of severe pulmonary hypertension secondary to connective tissue disease with continuous IV epoprostenol (prostacyclin). Chest 1998; 114(suppl):80S–82S 5 Sitbon O, Humbert M, Sanchez O, et al. Survival in pulmonary hypertension associated with connective tissue diseases (PH-CTD) treated with long-term epoprostenol (PGI2): comparison with primary pulmonary hypertension (PPH) [abstract]. Am J Respir Crit Care Med 1999; 159:A158
منابع مشابه
The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate
Introduction. Sepsis and its consequences such as metabolic acidosis are resulting in increased mortality. Although correction of metabolic acidosis with sodium bicarbonate seems a reasonable approach, there is ongoing debate regarding the role of bicarbonates as a therapeutic option. Methods. We conducted a PubMed literature search in order to identify published literature related to the effec...
متن کاملAlkali Therapy in Lactic Acidosis
This report attempts to frame the debate about clinical administration of sodium bicarbonate in the setting of lactic acidosis in terms of simple questions. Specifically, we address why we develop lactic acidosis in some circumstances, how acute lactic acidosis impairs cardiovascular function and why sodium bicarbonate may have deleterious effects which limit its utility. We also attempt to exp...
متن کاملCan sodium bicarbonate really help in treating metabolic acidosis caused by aluminium phosphide poisoning?
Management of aluminium phosphide (AlP) poisoning seems to have seen some changes over the recent years (1). We believe that one of the reasons was the review article (2) and letters to the editor (3-5) published in your journal between 2012 and 2013. However, we still face problems in treating severe cases, who generally present with refractory metabolic acidosis and whose prognosis is poor (6...
متن کاملIs there a role for sodium bicarbonate in treating lactic acidosis from shock?
PURPOSE OF REVIEW Bicarbonate therapy for severe lactic acidosis remains a controversial therapy. RECENT FINDINGS The most recent 2008 Surviving Sepsis guidelines strongly recommend against the use of bicarbonate in patients with pH at least 7.15, while deferring judgment in more severe acidemia. We review the mechanisms causing lactic acidosis in the critically ill and the scientific rationa...
متن کاملEffect of Sodium Bicarbonate Administration on Mortality in Patients with Lactic Acidosis: A Retrospective Analysis
BACKGROUND Lactic acidosis is a common cause of high anion gap metabolic acidosis. Sodium bicarbonate may be considered for an arterial pH <7.15 but paradoxically depresses cardiac performance and exacerbates acidosis by enhancing lactate production. This study aimed to evaluate the cause and mortality rate of lactic acidosis and to investigate the effect of factors, including sodium bicarbonat...
متن کاملAspirin-induced asthma and artificial flavors.
1 Rhee KH, Toro LO, McDonald GG, Nunnally RL, Levin DL. Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis: effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH. Chest 1993; 104:913-18 2 Sonett J, Baker LS, Hsi C, Knox MA, Visner MS, Landow L. Sodium bicarbonate versus carbicarb in canine myocardial hypercarbic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chest
دوره 118 3 شماره
صفحات -
تاریخ انتشار 2000